(2S)-4-Amino-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]buta... - Names and Identifiers
(2S)-4-Amino-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]buta... - Physico-chemical Properties
Molecular Formula | C19H20N2O4.HCl
|
Molar Mass | 377 |
Storage Condition | Sealed in dry,Room Temperature |
(2S)-4-Amino-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]buta... - Introduction
(2S)-4-Amino -2-[[(9H-Fluoren-9-ylmethoxy) carbonyl] amino] butanoic acid hydrochloride is a chemical substance with the following properties:
Physical and chemical properties:
-Appearance: White crystal or crystalline powder
-Molecular formula: C25H25N2O4 · HCl
-Molecular weight: 480.93g/mol
-melting point: about 160-165 ℃
-Solubility: Soluble in water and some organic solvents
Use:
-Biomedical Research: As an important amine protecting group, it is often used to change chemical properties, increase anti-metabolic ability and increase solubility in peptide synthesis and drug development.
-Pharmaceutical preparations: for the preparation of peptide drugs, peptide antibiotics and biologically active small molecules.
-Drug Guide: In drug delivery, it can improve drug selectivity and reduce toxicity.
Preparation Method:
The preparation method of (2S)-4-amino -2-[[(9H-fluoren-9-ylmethoxy) carbonyl] amino] butyric acid hydrochloride can be achieved by the following steps:
1. firstly, (9H-fluorene -9-yl formaldehyde) is added to dimethylformamide to obtain (9H-fluorene -9-yl methoxy) aldehyde.
2. condensation reaction of (9H-fluorene -9-ylmethoxy) aldehyde with formyl propyl amino acid to generate (2S)-4-amino -2-[[(9H-fluorene -9-ylmethoxy) carbonyl] amino] butyric acid.
3. finally, the obtained product is reacted with hydrochloric acid to prepare (2S)-4-amino -2-[[(9H-fluoren-9-ylmethoxy) carbonyl] amino] butyric acid hydrochloride.
Safety Information:
-Take appropriate safety precautions during operation and use, including wearing chemical protective gloves and glasses.
-Avoid inhalation of powder or contact with skin, avoid ingestion.
-In case of contact, rinse immediately with plenty of water and seek medical help.
-should be stored in a dry, well-ventilated place, away from fire and combustible materials.
-Detailed safety information can be found in the safety data sheet of the chemical.
Last Update:2024-04-09 15:17:58